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Protocol No.1533GCCPrincipal InvestigatorRao, Gautam
PhasePhase II (Cancer Control)
Age GroupAdult
TitleA Randomized, Double-blind, Placebo-Controlled, Phase 2 Study to Assess the Efficacy and Safety of Farletuzumab (MORAb-003) in Combination with Carboplatin plus Paclitaxel or Carboplatin plus Pegylated Liposomal Doxorubicin (PLD) in Subjects with Low CA125 Platinum-Sensitive Ovarian Cancer
DescriptionThis study will only include subjects who have platinum sensitive relapsed epithelial ovarian cancer [meaning your ovarian cancer did not return for at least 6 months after your first treatment with chemotherapy containing platinum (carboplatin or cisplatin)]. CA125 is a protein that is found in the blood of most ovarian cancer subjects. Subjects will only be included in this study if their CA125 test result does not exceed a certain level.
TreatmentCarboplatin plus paclitaxel or carboplatin plus Pegylated Liposomal Doxorubicin (PLD), given with an investigational drug called farletuzumab or a placebo.
Key EligibilityPlease refer to www.clinicaltrials.gov for more information

ClinicalTrials.gov Identifier: NCT02289950
Applicable Disease SitesOvary
Therapies InvolvedChemotherapy (NOS)
Chemotherapy multiple agents systemic
Immunotherapy
Drugs InvolvedMORab-003 (Farletuzumab)
PACLITAXEL
Placebo
Taxol (PACLITAXEL)
carboplatin
doxorubicin pegylated liposome (PLD)
StatusOpen
Treatment TypeTreatment
ClinicalTrials.gov http://www.clinicaltrials.gov/ct2/show/NCT02289950
ContactGreenebaum Cancer Center Maha Khalil, PhD Phone:410-328-5009
Pager:
Email:mkhalil@umm.edu
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