| 10492 | 10492: Phase 1/1b Study of AKT Inhibitor Ipatasertib with Chemoradiation for Locally Advanced Head and Neck Cancer | Open |
| 1563GCC | Mitigation of radiation pneumonitis and fibrosis | Open (affiliates only) |
| 1635GCC | Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature in Lung Stereo-tactic Ablative Body Radiotherapy (SAbR)
| Open |
| 19140GCCC | PILOT STUDY OF LASER INTERSTITIAL THERMAL THERAPY FOLLOWED BY HYPOFRACTIONATED RADIATION THERAPY FOR RECURRENT HIGH GRADE GLIOMAS | Open |
| 20138GCC | LASER INTERSTITIAL THERMAL THERAPY FOLLOWED BY HYPOFRACTIONATED RADIATION THERAPY FOR TREATMENT OF NEWLY DIAGNOSED HIGH-GRADE GLIOMAS | Open |
| 21136GCC | Phase 2 randomized Total Eradication of metastatic lesions following definitive Radiation to the Prostate in de novo oligometaStatic prostate cancer (TERPS) trial
| Open |
| 2242GCCC | Hybrid Virtual MRI/CBCT for Image Guidance in Liver Radiation Therapy | Open |
| 2261GCCC | 2261GCCC: A Phase III, double-blind, placebo-controlled, Randomised, Multicentre, International Study of Durvalumab Plus Oleclumab and Durvalumab Plus Monalizumab in Patients With Locally Advanced (Stage III), Unresectable Non-small Cell Lung Cancer (NSCLC) Who Have Not Progressed Following Definitive, Platinum-Based Concurrent Chemoradiation Therapy (PACIFIC 9) | Open |
| 2379GCC | IImplications of Religious Beliefs, Mistrust and Other Psychosocial, Demographic and Economic Variables Influencing a Patient’s Decision on Enrolling in Radiation-Specific Cancer Trials | Open |
| A011502 | Aspirin in Preventing Recurrence of Cancer in Patients With Node Positive HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy | Open (affiliates only) |
| N1048 | PROSPECT: A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision | Open (affiliates only) |
| NRG-BN012 | A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients with Resectable Brain Metastases | Open |
| NRG-LU007 | Randomized Phase II/III Trial of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR Trial | Open |